Both clubs are merely hoping to delay the inevitable in the league, with United set to watch their city rivals lift the Premier League crown and West Brom going down a division.
The Red Devils should be confident of taking the three points against a side shipping goals and on their third coach of the season, but Jose Mourinho expects a tough tie.
“I think [it will be] a big challenge because they know that in football anything is possible until mathematically it is impossible,” he told reporters.
Everybody knows, they know and they still smell a chance, but every match that is played, if they don’t get points, then they are closer to relegation, but I think they still believe that mathematically it’s possible.
“In our case, we come from a big result and during the week I was trying to fight that result by working well and hard and trying to make the players understand that it’s not enough to deserve to finish second, we need the points to finish second and obviously to finish top four we need four or five points. But to finish second we need much more than that and after three important points last weekend we have to try to do this three and be closer to the end of the season and to the second position which, in this moment, is our ambition.”
Manchester City currently holds a 16point lead over Manchester United though haven played a game more.
Jose Mourinho would have love a Tottenham win but City got back to their winning ways with a 3-1 win at Wembley stadium yesterday.
MANCHESTER UNITED; De Gea, Romero, Pereira, Bailly, Blind, Darmian, Jones, Lindelof, Rojo, Shaw, Smalling, Valencia, Carrick, Fellaini, Gomes, Hamilton, Herrera, Lingard, Mata, Matic, McTominay, Pogba, Young, Sanchez, Lukaku, Martial, Rashford
The recent return to the squad of Daley Blind, Phil Jones, Marcos Rojo and Marouane Fellaini means that goalkeeper Sergio Romero is the only question mark for Jose Mourinho.
Predicted XI: De Gea; Valencia, Smalling, Bailly, Young; Herrera, Matic, Pogba Lingard, Sanchez; Lukaku.
WESTBROM ALBION; Foster, Myhill, Palmer, Nyom, Gibbs, Evans, Gabr, McAuley, Dawson, Hegazi, Yacob, Morrison, Livermore, Phillips, Brunt, McClean, Burke, Barry, Krychowiak, Chadli, Field, Harper, Robson-Kanu, Rondon, Sturridge, Rodriguez, Leko
James Morrison remains out of action for the Baggies, while Jonny Evans and Gareth Barry are doubtful, but Nacer Chadli, Sam Field and Daniel Sturridge could be back in the squad.
Predicted XI: Foster, Dawson, Hegazi, Evans, Gibbs; Phillips, Livermore, Brunt, McClean; Rodriguez, Rondon.